LL-37

Innate Immunity & Tissue Repair Research Peptide

LL-37 is a naturally occurring antimicrobial peptide derived from the human cathelicidin protein family, playing a critical role in the body’s
innate immune defense system.

It is widely studied for its ability to combat microbial threats, regulate inflammatory responses, and promote tissue repair.
LL-37 is expressed in various cells including immune cells, epithelial tissues, and skin, where it contributes to
barrier protection and healing processes.

Its multifunctional biological activity makes LL-37 a key research compound in immune resilience, skin regeneration, and recovery-focused protocols.

Product features

• Human-derived antimicrobial peptide involved in innate immune defense.
• 5 mg high-purity LL-37 per vial.
• Lyophilized (freeze-dried) for enhanced stability and shelf life.
• Sterile depyrogenated glass vial for precise research handling.
• Butyl rubber stopper allows repeated access without compromising integrity.
• Tamper-evident sealed vial ensuring consistency and quality.

Key benefits (Research Highlights)

• Broad-spectrum antimicrobial activity — studied against bacteria, viruses, and fungi.
• Immune system modulation — supports balanced inflammatory response.
• Enhanced tissue repair — promotes wound healing and cellular regeneration.
• Skin & barrier protection — supports epithelial integrity and recovery.
• Anti-inflammatory signaling — helps regulate excessive immune responses.
• Recovery-focused support — studied in injury and healing models.

Research reference: biological mechanism

LL-37 functions as a cationic host defense peptide that interacts directly with microbial membranes, leading to pathogen disruption.
It also influences immune signaling pathways, including cytokine modulation and chemotaxis of immune cells.

Additionally, LL-37 plays a role in angiogenesis, epithelial cell migration, and tissue remodeling—key processes involved in wound healing and recovery.

Research reference: immune & regenerative findings

• Demonstrates antimicrobial effects against a broad range of pathogens
• Supports wound closure and tissue regeneration in experimental models
• Modulates inflammatory cytokine expression
• Investigated for skin conditions, infections, and immune dysfunction

Research reference: dosage exploration & applications

LL-37 is studied across various research models focusing on immune response, infection control, and tissue repair.
Applications range from localized tissue studies to broader systemic immune investigations.

• Commonly explored in short to medium-term recovery studies
• Investigated in skin, wound healing, and immune protocols
• Compatible with regenerative and recovery-focused research stacks

Research reference: safety profile

LL-37 is generally well-tolerated in controlled research settings. Effects are dependent on concentration and exposure models.

• Localized irritation in high-concentration studies
• Inflammatory response variations depending on dosing models
• Requires controlled handling in experimental environments

Disclaimer: For research purposes only. Not intended for human consumption. This product is not intended to diagnose, treat, cure, or prevent any disease.